Triple negative breast cancer (TNBC) is one of many forms of breast cancer.
Forms of breast cancer are generally diagnosed based on the presence or absence of three “receptors” known to fuel most breast cancer tumors: estrogen, progesterone and HER2‐neu.
A diagnosis of TNBC means that the tumor in question is estrogen‐receptor negative, progesterone‐receptor negative and Her2‐negative. In other words, triple negative breast cancer tumors do not exhibit any of the three known receptors.
Receptor‐targeting therapies have fueled tremendous recent advances in the fight against breast cancer. Unfortunately, there is no such targeted therapy for triple negative breast cancer.
TNBC tends to be more aggressive, more likely to recur, and more difficult to treat because there is no targeted treatment.
TNBC disproportionately strikes younger women, African American women, and those with BRCA1 mutations.
Approximately every half hour, another woman in the US is diagnosed with triple negative breast cancer.
About the Triple Negative Breast Cancer Foundation
Triple Negative Breast Cancer Foundation (TNBCF) was founded in 2006 in honor of Nancy Block‐Zenna, who was diagnosed at the young age of 35 with triple negative breast cancer before succumbing to the disease in 2007. In response to Nancy’s diagnosis, her friends identified a dire need to create a central source of information for this dangerous and aggressive form of breast cancer, about which little was known just a short time ago. It is the Foundation’s mission to be a credible source for triple negative breast cancer information, a catalyst for science and patient advocacy groups, and a caring community with meaningful services for patients and their families. TNBCF supports the triple negative breast cancer community in many ways, including:
We host regular “think tanks” which are attended by the top doctors and researchers in the field, to create roadmaps for a cure for triple negative breast cancer.
We offer significant research grant support to encourage the launch of projects aimed at finding targeted treatments for triple negative disease. TNBCF grant support has been offered to researchers at leading institutions including Stanford, Memorial Sloan‐Kettering Cancer Center, University of North Carolina, NYU, Mount Sinai, The Institute of Cancer Research (London), University of Alabama, University of Miami, Whitehead Institute For Biomedical Research, and others.
We co‐sponsored a $6.4 million Promise Grant with Susan G. Komen for the Cure, aimed at finding targeted therapy for triple negative disease.
We offer a financial assistance program to help women with triple negative breast cancer afford transportation, child care and other expenses associated with their treatment.
We continuously expand our website, www.tnbcfoundation.org, and offer an evergrowing resources section and up‐to‐the‐minute information about the disease.
We host online forums which offer the TNBC community a central place to go for support and information about the disease. Our forums have over 7400 active members, who have posted over 125,000 posts on more than 12,000 topics.
We offer a TNBC Helpline, where patients can call and speak with oncology social workers specifically trained to address the needs of the triple negative breast cancer community.
We constantly work to educate patients about triple negative breast cancer through multiple live conferences, teleconferences and webinars, and with printed and online materials that have proven to be essential resources for patients.
We work to educate doctors and nurses about triple negative breast cancer through Continuing Medical Education programs aimed at improving patients’ experience during treatment.
We fund a patient navigator at Jacobi Medical Center in New York to help guide triple negative breast cancer patients through treatment.
We fund programs at local hospitals to address the psychosocial aspects of women living with a diagnosis of triple negative breast cancer.
We founded and host TNBC Day, the only global event dedicated to raising awareness of triple negative disease and funds for TNBC‐specific research. Our TNBC Day campaign has resulted in hundreds of grassroots events, extremely high social media engagement, significant media attention, and successful fundraising to further our mission.